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Product Details
TA502357
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:2,000 | - |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:150 | - |
Immunocytochemistry (ICC/IF) |
1:100 | - |
Flow Cytometry (Flow) |
1:100 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human |
Host/Isotype |
Mouse / IgG1 |
Class |
Monoclonal |
Type |
Antibody |
Clone |
OTI2D10 |
Immunogen |
Full length human recombinant protein of human AQP1 produced in HEK293T cell. |
Conjugate |
Unconjugated |
Form |
liquid |
Concentration |
0.47 mg/mL |
Purification |
Affinity chromatography |
Storage buffer |
PBS with 1% BSA, 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20° C, Avoid Freeze/Thaw Cycles |
Target Information
Aquaporin 1 is a 28kD integral membrane protein which was originally identified in red blood cells and renal proximal tubules. AQP1 is also expressed by the choroid plexus and various other tissues. It forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: AQP 1; AQP CHIP; AQP-1; aquaporin 1 (channel-forming integral protein, 28kDa, CO blood group); aquaporin 1, Colton blood group antigen; Aquaporin CHIP; Aquaporin-1; Aquaporin-CHIP; Aquaporin1; channel-like integral membrane protein, 28-kDa; CHIP 28; Colton blood group; MGC26324; Urine water channel; Water channel protein for red blood cells and kidney proximal tubule
Gene Aliases: AQP-CHIP; AQP1; CHIP28; CO
UniProt ID: (Human) P29972
Entrez Gene ID: (Human) 358
Molecular Function:
transporter
renal water homeostasis
renal water transport
cGMP biosynthetic process
potassium ion transport
water transport
cell volume homeostasis
cellular water homeostasis
carbon dioxide transport
ammonium transport
bicarbonate transport
glycerol transport
cellular homeostasis
lateral ventricle development
pancreatic juice secretion
nitric oxide transport
establishment or maintenance of actin cytoskeleton polarity
cerebrospinal fluid secretion
cellular response to stress
cellular response to UV
transepithelial water transport
carbon dioxide transmembrane transport
odontogenesis
response to drug
negative regulation of apoptotic process
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of angiogenesis
positive regulation of saliva secretion
positive regulation of fibroblast proliferation
multicellular organismal water homeostasis
cellular response to hydrogen peroxide
cellular response to inorganic substance
cellular response to mechanical stimulus
cellular response to copper ion
cellular response to mercury ion
cellular response to retinoic acid
cellular response to cAMP
cellular response to hypoxia
cellular response to salt stress
cellular hyperosmotic response
cellular response to dexamethasone stimulus
cellular response to nitric oxide
potassium ion transmembrane transport
ammonium transmembrane transport
maintenance of symbiont-containing vacuole by host
intracellular cGMP activated cation channel activity
potassium channel activity
water transmembrane transporter activity
protein binding
ammonium transmembrane transporter activity
potassium ion transmembrane transporter activity
glycerol transmembrane transporter activity
water channel activity
glycerol channel activity
transmembrane transporter activity
nitric oxide transmembrane transporter activity
carbon dioxide transmembrane transporter activity
Performance Guarantee
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