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Invitrogen
ARFGEF2 Recombinant Rabbit Monoclonal Antibody (24GB6840)
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FIGURE: 1 / 1
ARFGEF2 Antibody (MA5-56969) in WB
Western blot analysis of ARFGEF2. Total cell lysates (30 μg) from C2C12, H9c2, HAP-1, HeLa, HepG2, and HT-1080 cell lines were loaded and separated by SDS-PAGE. The blot was incubated with ARFGEF2 Recombinant Monoclonal Antibody (Product # MA5-56969) at a 1:5,000 dilution and HRP-conjugated goat anti-rabbit secondary antibody at a 1:20,000 dilution respectively.
Product Details
MA5-56969
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293F
Class
Recombinant Monoclonal
Type
Antibody
Clone
24GB6840
Immunogen
A synthesized peptide derived from human ARFGEF2 (aa 1501-1514)
Conjugate
Form
Liquid
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Dry ice (international)
RRID
Target Information
ADP-ribosylation factors (ARFs) play an important role in intracellular vesicular trafficking. The protein encoded by this gene is involved in the activation of ARFs by accelerating replacement of bound GDP with GTP and is involved in Golgi transport. It contains a Sec7 domain, which may be responsible for its guanine-nucleotide exchange activity and also brefeldin A inhibition. [provided by RefSeq, Jul 2008].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ADP-ribosylation factor guanine nucleotide-exchange factor 2; ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited); Brefeldin A-inhibited GEP 2; Brefeldin A-inhibited guanine nucleotide-exchange factor 2; Brefeldin A-inhibited guanine nucleotide-exchange protein 2
Gene Aliases: AI463430; ARFGEF2; ARFGEP2; AW493672; BIG2; dJ1164I10.1; E230011G24Rik; PVNH2
UniProt ID: (Human) Q9Y6D5, (Mouse) A2A5R2, (Rat) Q7TSU1
Entrez Gene ID: (Human) 10564, (Mouse) 99371, (Rat) 296380
receptor recycling
exocytosis
Golgi to plasma membrane transport
endosome organization
endomembrane system organization
protein transport
regulation of ARF protein signal transduction
positive regulation of tumor necrosis factor production
intracellular signal transduction
positive regulation of GTPase activity
transport
vesicle-mediated transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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