|Immunocytochemistry (ICC)||1 ug/ml|
|Immunohistochemistry (Paraffin) (IHC (P))||5 ug/ml|
|Western Blot (WB)||1 ug/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Purified human AGR3 protein|
|Storage buffer||PBS with 0.2% BSA|
|Contains||15mM sodium azide|
|Storage conditions||4° C, do not freeze|
This antibody recognizes the PLMII epitope of AGR3 (AG3) and AGR2 (AG2) proteins.
AGR2 (Anterior Gradient 2), also known as AG2 (hAG-2, HAG2 in human), or GOB-4, and AGR3 (Anterior Gradient 3), also known as AG3 (hAG-3, HAG3 in human), or BCMP11, are secreted cytoplasmic proteins which are involved in metastasis induction and p53 tumour supressor inhibition. They may serve as molecular markers and potential therapeutic targets for hormone-responsive breast tumours; AGR2 was reported also as a marker of other carcinomas. Xenopus homolog of these proteins is associated with anteroposterior fate determination during early development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: AG-2; AG-3; AG2; AGR2; AGR3; anterior gradient 2 homolog; Anterior gradient 3 homolog; anterior gradient homolog 2; anterior gradient homolog 3; Anterior gradient protein 2 homolog; Anterior gradient protein 3; Anterior gradient protein 3 homolog; BCMP11; Breast cancer membrane protein 11; epididymis secretory protein Li 116; GOB-4; HAG-2; hAG-3; HPC8; member 17; PDIA17; protein disulfide isomerase family A; protein disulfide isomerase family A, member 17; Protein disulfide isomerase family A, member 18; secreted cement gland homolog; Secreted cement gland protein XAG-2 homolog; UNQ515/PRO1030; UNQ642/PRO1272
Gene Aliases: AG-3; AG2; AG3; AGR2; AGR3; BCMP11; GOB-4; HAG-2; hAG-3; HAG3; HEL-S-116; PDIA17; PDIA18; UNQ515/PRO1030; UNQ642/PRO1272; XAG-2
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