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OriGene
ARHGDIA Monoclonal Antibody (OTI1F2), TrueMAB™
Advanced Verification
This Antibody was verified by Knockout to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 7
ARHGDIA Antibody (TA501089) in WB
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ARHGDIA (RC200902, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-ARHG. Positive lysates LY401371 (100 µg) and LC401371 (20 µg) can be purchased separately from OriGene.
Product Details
TA501089
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Dog,
Human,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
OTI1F2
Immunogen
Full length human recombinant protein of human ARHGDIA produced in HEK293T cell.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 1% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Aplysia Ras-related homologs (ARHs), also called Rho genes, belong to the RAS gene superfamily encoding small guanine nucleotide exchange (GTP/GDP) factors. The ARH proteins may be kept in the inactive, GDP-bound state by interaction with GDP dissociation inhibitors, such as ARHGDIA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: arhgdia {ECO:0000312|RGD:1359547}; epididymis secretory sperm binding protein Li 47e; GDP-dissociation inhibitor, aplysia RAS-related 1; MGC117248; Rho GDI 1; rho GDI 1 {ECO:0000250|UniProtKB:P19803}; Rho GDP dissociation inhibitor (GDI) alpha; Rho GDP-dissociation inhibitor 1; rho GDP-dissociation inhibitor 1 {ECO:0000250|UniProtKB:P19803}; Rho-GDI alpha; rho-GDI alpha {ECO:0000250|UniProtKB:P19803}
Gene Aliases: ARHGDIA; Bles01; GDIA1; HEL-S-47e; NPHS8; RHOGDI; RHOGDI-1
UniProt ID: (Human) P52565, (Rat) Q5XI73
Entrez Gene ID: (Human) 396, (Dog) 475924, (Rat) 360678
movement of cell or subcellular component
negative regulation of cell adhesion
regulation of Rho protein signal transduction
negative regulation of apoptotic process
positive regulation of GTPase activity
negative regulation of axonogenesis
positive regulation of axonogenesis
regulation of small GTPase mediated signal transduction
semaphorin-plexin signaling pathway
regulation of actin cytoskeleton reorganization
Rho protein signal transduction
regulation of cell shape
negative regulation of cell migration
regulation of protein localization
regulation of catalytic activity
cellular response to mechanical stimulus
cellular response to organic cyclic compound
cellular response to redox state
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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