Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Dilute in PBS (pH7.3) if necessary. Stable for 12 months from date of receipt.
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate Rho-dependent signals. This protein is similar to rat collybistin protein. Alternative splicing of this gene generates two transcript variants which encode different isoforms. Also there is possibility for the usage of multiple polyadenylation sites for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: APC-stimulated guanine nucleotide exchange factor; APC-stimulated guanine nucleotide exchange factor 1; Asef; DKFZp434G2016; Rho guanine nucleotide exchange factor (GEF) 4; Rho guanine nucleotide exchange factor 4
Gene Aliases: 9330140K16Rik; ARHGEF4; ASEF; ASEF1; ENSMUSG00000070955; GEF4; KIAA1112; STM6
UniProt ID: (Human) Q9NR80, (Mouse) Q7TNR9
Entrez Gene ID: (Human) 50649, (Rat) 301334, (Mouse) 226970
Molecular Function:
G-protein modulator
protein-binding activity modulator
guanyl-nucleotide exchange factor
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