Sequence of this protein is as follows: MAKDFQDIQQ LSSEENDHPF HQGPPPAQPL AQRLCSMVCF SLLALSFNIL LLVVICVTGS QSAQLQAELR SLKEAFSNFS SSTLTEVQAI STHGGSVGDK ITSLGAKLEK QQQDLKADHD ALLFHLKHFP VDLRFVACQM ELLHSNGSQR TCCPVNWVEH QGSCYWFSHS GKAWAEAEKY CQLENAHLVV INSWEEQRFI VQHTNPFNTW IGLTDSDGSW KWVDGTDYRH NYKNWAVTQP DNWRGHELGG SEDCVEVQPD GRWNDDFCLQ VYRWVCEKRR NATGEVA
ASGR2 is a cell surface receptor that binds to galactose-terminated glycoproteins. It transports these glycoproteins via a series of membrane vesicles and tubules to an acidic-sorting organelle where the receptor and ligand dissociates. Then the receptor is recycled back to the cell surface. There are four alternatively spliced transcript variants of this gene. This gene has multiple polyadenylation sites.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ANCO-2; ANCO1; ASGP-R 2; Asialoglycoprotein receptor 2; C-type lectin domain family 4 member H2; GAC-1; HBxAg-binding protein; Hepatic lectin H2; HL-2; Nbla00144
Gene Aliases: ASGP-R2; ASGPR2; ASGR2; CLEC4H2; HBXBP; HL-2
UniProt ID: (Human) P07307
Entrez Gene ID: (Human) 433
Molecular Function: membrane traffic protein