MA5-17033 targets ASS1 in FACS, ICC, IF and WB applications and shows reactivity with Human, Mouse, Non-human primate, and Rat samples.
The MA5-17033 immunogen is purified recombinant fragment of human ASS1 expressed in E. Coli.
MA5-17033 detects ASS1 which has a predicted molecular weight of approximately 47kDa.
The protein encoded by this gene catalyzes the penultimate step of the arginine biosynthetic pathway. There are approximately 10 to 14 copies of this gene including the pseudogenes scattered across the human genome, among which the one located on chromosome 9 appears to be the only functional gene for argininosuccinate synthetase. Mutations in the chromosome 9 copy of ASS cause citrullinemia. Two transcript variants encoding the same protein have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Argininosuccinate synthase; argininosuccinate synthetase 1; arginosuccinate synthetase 1; Citrulline--aspartate ligase; citrulline-aspartate ligase; RP11-618A20.2
Gene Aliases: AA408052; ASS; Ass-1; ASS1; ASSA; CTLN1; fold
Molecular Function: ligase