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Product Details
MA5-34916
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
11F1
Immunogen
Recombinant protein within Human ASS1 aa 1-412
Conjugate
Unconjugated
Form
Liquid
Concentration
2 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol, 0.2% BSA
Contains
0.05% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles, store in dark
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2848822
Product Specific Information
Positive Control: HepG2, MCF-7, SiHa, human colon cancer tissue, mouse testis tissue.
Target Information
The protein encoded by this gene catalyzes the penultimate step of the arginine biosynthetic pathway. There are approximately 10 to 14 copies of this gene including the pseudogenes scattered across the human genome, among which the one located on chromosome 9 appears to be the only functional gene for argininosuccinate synthetase. Mutations in the chromosome 9 copy of ASS cause citrullinemia. Two transcript variants encoding the same protein have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Argininosuccinate synthase; argininosuccinate synthetase 1; Citrulline--aspartate ligase; citrulline-aspartate ligase; RP11-618A20.2
Gene Aliases: ASS; ASS1; CTLN1
UniProt ID: (Human) P00966
Entrez Gene ID: (Human) 445
urea cycle
citrulline metabolic process
argininosuccinate metabolic process
kidney development
liver development
arginine biosynthetic process
aspartate metabolic process
acute-phase response
midgut development
aging
response to nutrient
response to zinc ion
response to mycotoxin
response to estradiol
response to drug
positive regulation of nitric oxide biosynthetic process
response to growth hormone
diaphragm development
response to fatty acid
cellular response to lipopolysaccharide
cellular response to amino acid stimulus
cellular response to ammonium ion
cellular response to cAMP
cellular response to interferon-gamma
cellular response to tumor necrosis factor
cellular response to glucagon stimulus
cellular response to oleic acid
cellular response to amine stimulus
cellular response to laminar fluid shear stress
cellular response to dexamethasone stimulus
negative regulation of leukocyte cell-cell adhesion
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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