APG12 is required for autophagy. APG5 conjugates to ATG12 and associates with isolation membrane to form cup-shaped isolation membrane and autophagosome. The conjugate detaches from the membrane immediately before or after autophagosome formation is completed.
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Protein Aliases: Apg12 (autophagy, yeast) homolog; APG12-like; ATG12 autophagy related 12 homolog; autophagy-related 12; Autophagy-related protein 12; Ubiquitin-like protein ATG12
Gene Aliases: 4931423H11Rik; A330058M13Rik; APG12; APG12L; ATG12; Atg12l; FBR93; HAPG12