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|Tested species reactivity||Fruit fly, Human, Mouse, Rat, Clawed frog|
|Host / Isotype||Mouse / IgG1|
|Clone||F38 P7 H9|
|Immunogen||Synthetic peptide, conjugated to Ovalbumin, corresponding to residues A(583) H T N L R L F H H(592) of human ATIC.|
|Storage buffer||PBS with 1mg/ml BSA|
|Contains||0.05% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||1µg per 10^6 cells|
|Immunofluorescence (IF)||Assay Dependent|
|Immunohistochemistry (Paraffin) (IHC (P))||5 ug/mL|
|Western Blot (WB)||2 ug/mL|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA1-086 detects the ATIC in human, rat, Xenopus, Drosophila, and mouse cells.
MA1-086 has been successfully used in Western blot and immunohistochemistry (parrafin) procedures. By Western blot, this antibody detects a ~64.6 kDa protein.
The MA1-086 immunogen is a synthetic peptide, conjugated to Ovalbumin, corresponding to residues A(583) H T N L R L F H H(592) of human ATIC..
ATIC is a 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase which helps catalyze the penultimate and final steps of the de novo purine biosynthetic pathway. The human ATIC cDNA encodes a deduced 591-amino acid protein that is 81% identical to the chicken sequence.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase; 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase; 5-aminoimidazole-4-carboxamide-1-beta-D-ribonucleotide transformylase/inosinicase; AICAR formyltransferase/IMP cyclohydrolase bifunctional enzyme; AICARFT/IMPCHASE; bifunctional purine biosynthesis protein PURH; CG11089-PA; CG11089-PB; epididymis secretory sperm binding protein Li 70p; phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; uncharacterized protein
153761_at; 2610509C24Rik; AA536954; AICAR; AICARFT; ATIC; AW212393; BEST:GH11240; CT30991; Dmel\CG11089; Dmel_CG11089; HEL-S-70p; IMPCHASE; OK/SW-cl.86; PURH