This Antibody was verified by KnockDown to ensure that the antibody binds to the antigen stated. View Details
MA1-086 detects the ATIC in human, rat, Xenopus, Drosophila, and mouse cells.
MA1-086 has been successfully used in Western blot and immunohistochemistry (parrafin) procedures. By Western blot, this antibody detects a ~64.6 kDa protein.
The MA1-086 immunogen is a synthetic peptide, conjugated to Ovalbumin, corresponding to residues A(583) H T N L R L F H H(592) of human ATIC..
ATIC is a 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase which helps catalyze the penultimate and final steps of the de novo purine biosynthetic pathway. The human ATIC cDNA encodes a deduced 591-amino acid protein that is 81% identical to the chicken sequence.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase; 5-aminoimidazole-4-carboxamide-1-beta-D-ribonucleotide transformylase/inosinicase; AICAR formyltransferase/IMP cyclohydrolase bifunctional enzyme; AICAR transformylase; AICARFT/IMPCHASE; ATIC; Bifunctional purine biosynthesis protein PURH; Bifunctional purine biosynthesis protein PURH, N-terminally processed; CG11089-PA; CG11089-PB; epididymis secretory sperm binding protein Li 70p; IMP cyclohydrolase; IMP synthase; Inosinicase; Phosphoribosylaminoimidazolecarboxamide formyltransferase; phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; uncharacterized protein
Gene Aliases: 153761_at; 2610509C24Rik; AA536954; AICAR; AICARFT; ATIC; AW212393; BEST:GH11240; CT30991; Dmel\CG11089; Dmel_CG11089; HEL-S-70p; IMPCHASE; OK/SW-cl.86; PURH; XELAEV_18044849mg