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Invitrogen
ATIC Monoclonal Antibody (F38 P7 H9)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA1-086
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Fruit fly,
Human,
Mouse,
Rat,
Xenopus
Published species
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
F38 P7 H9
Immunogen
Synthetic peptide, conjugated to Ovalbumin, corresponding to residues A(583) H T N L R L F H H(592) of human ATIC.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein G
Storage buffer
PBS with 1mg/mL BSA
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
MA1-086 detects the ATIC in human, rat, Xenopus, Drosophila, and mouse cells.
MA1-086 has been successfully used in Western blot and immunohistochemistry (parrafin) procedures. By Western blot, this antibody detects a ~64.6 kDa protein.
The MA1-086 immunogen is a synthetic peptide, conjugated to Ovalbumin, corresponding to residues A(583) H T N L R L F H H(592) of human ATIC..
Target Information
ATIC is a 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase which helps catalyze the penultimate and final steps of the de novo purine biosynthetic pathway. The human ATIC cDNA encodes a deduced 591-amino acid protein that is 81% identical to the chicken sequence.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 5-aminoimidazole-4-carboxamide-1-beta-D-ribonucleotide transformylase/inosinicase; AICAR formyltransferase/IMP cyclohydrolase bifunctional enzyme; AICAR transformylase/inosine monophosphate cyclohydrolase; bifunctional purine biosynthesis protein PURH; bifunctional purine biosynthesis protein PURH-like; epididymis secretory sperm binding protein Li 70p; phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; unnamed protein product
Gene Aliases: 2610509C24Rik; AICAR; AICARFT; atic; HEL-S-70p; IMPCHASE; PURH; XELAEV_18044849mg
UniProt ID: (Human) P31939, (Mouse) Q9CWJ9, (Rat) O35567
Entrez Gene ID: (Human) 471, (Mouse) 108147, (Rat) 81643, (Xenopus) 735175
brainstem development
nucleobase-containing compound metabolic process
purine nucleotide biosynthetic process
GMP biosynthetic process
'de novo' IMP biosynthetic process
cerebellum development
cerebral cortex development
organ regeneration
'de novo' AMP biosynthetic process
dihydrofolate metabolic process
tetrahydrofolate biosynthetic process
'de novo' XMP biosynthetic process
cellular response to interleukin-7
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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