Note: You clicked on an external link, which has been disabled in order to keep your shopping session open.
Fixed and permeabilized bovine pulmonary artery endothelial cells stained with Mouse anti ATP Synthase Subunit IF1 Monoclonal Antibody (Cat. no. A21355), which highlights the mitochondria. The antibody was prelabeled with the Zenon® Alexa Fluor® 488 Mouse IgG1 Labeling Kit (Cat. no. Z25002).
|Tested species reactivity||Mouse , Rat , Human , Cattle|
|Published species reactivity||Primate , Mouse|
|Host / Isotype||Mouse / IgG1|
|Storage buffer||PBS, pH 7.4|
|Contains||0.1% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Western Blot (WB)||1.0 ug/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
ATP synthase is extremely conserved through evolution and can be found in plants, fungi, bacteria, and animals. The ATP synthase enzyme is a transmembrane protein responsible for driving the reversible reaction from ADP+ phosphate to ATP. This reaction is accomplished by a flux of protons across the membrane as a result of electron transfer. The ATP synthase protein has two main sections; the F1 ATP-ase (soluble) and the F0 ATP-ase (membrane embedded). The F1 section consists of the alpha, beta, gamma, delta, and epsilon subunits. While the F0 consists of a, b, and c subunits.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Arenavirus infection induces discrete cytosolic structures for RNA replication.
A-21355 was used in western blot to identify and study cytosolic structures involved in arenavirus replication and transcription.
|Baird NL,York J,Nunberg JH||Journal of virology (86:11301)||2012|
Mitochondrial DNA toxicity compromises mitochondrial dynamics and induces hippocampal antioxidant defenses.
A-21355 was used in immunohistochemistry - paraffin section to investigate the effects of mitochondrial DNA damage on hippocampal neurons.
|Lauritzen KH,Cheng C,Wiksen H,Bergersen LH,Klungland A||DNA repair (10:639)||2011|
If1, IF(1), IF1PA, BOS_2311, Atpi, RP5-1092A3.1, IP, ATPI, ATPIP
ATPase inhibitor, mitochondrial, IF(1), IF1, inhibitor of F(1)F(o)-ATPase, ATP synthase inhibitor protein, ATPase inhibitor protein, ATPase inhibitor (rat mitochondrial IF1 protein), ATPase inhibitor mitochondrial, ATPIF1, ATPI