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|Tested species reactivity||Human , Primate|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Purified recombinant fragment of ATP2C1 expressed in E. Coli.|
|Contains||0.03% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Immunohistochemistry (IHC)||1/200 - 1/1000|
|Western Blot (WB)||1/500 - 1/2000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA5-15592 targets ATP2C1 in IHC and WB applications and shows reactivity with Human and Non-human primate samples.
The MA5-15592 immunogen is purified recombinant fragment of ATP2C1 expressed in E. Coli.
MA5-15592 detects ATP2C1 which has a predicted molecular weight of approximately 100kDa.
The protein encoded by this gene belongs to the family of P-type cation transport ATPases. This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of the calcium. Defects in this gene cause Hailey-Hailey disease, an autosomal dominant disorder. Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
ATP2C1A, BCPM, SPCA1, HUSSY-28, PMR1, hSPCA1, HHD
ATP-dependent Ca(2+) pump PMR1, ATPase 2C1, ATPase, Ca(2+)-sequestering, HUSSY-28, calcium-transporting ATPase type 2C member 1, secretory pathway Ca2+/Mn2+ ATPase 1, HHD, BCPM, PMR1, SPCA1, hSPCA1, ATP2C1A, KIAA1347, ATP2C1