ATRIP is an 86 kDa protein that is phosphorylated by ATR, regulates ATR expression, and is an essential component of the DNA damage checkpoint pathway. It localizes to the intranuclear foci after DNA damage or inhibition of replication.
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Protein Aliases: ATM and Rad3-related-interacting protein; ATR interacting protein; ATR-interacting protein; three prime repair exonuclease 1
Gene Aliases: AGS1; ATRIP; TREX1
UniProt ID: (Human) Q8WXE1