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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 46 and 308 of Human Abin 2|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 10% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-28918 targets Abin 2 in IF, IHC (P), and WB applications and shows reactivity with Human samples.
The PA5-28918 immunogen is recombinant fragment corresponding to a region within amino acids 46 and 308 of Human Abin 2.
TNIP2 binds to the C-terminal zinc finger domain of A20 (TNFAIP3; MIM 191163) and is involved in activation of the ERK (see MAPK3; MIM 601795) MAP kinase pathway in various cell types (Van Huffel et al., 2001 [PubMed 11390377]; Papoutsopoulou et al., 2006 [PubMed 16633345]).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
A20-binding inhibitor of NF-kappaB activation-2; ABIN2; fetal liver LKB1-interacting protein; FLIP1; KLIP; TNIP2
ABIN2; FLIP1; KLIP; TNIP2