|Tested species reactivity||Bovine, Human, Pig|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to residues 40-80 of human ACP1.|
|Storage buffer||PBS with 0.2% gelatin|
|Contains||0.05% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||1-3 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-41703 detects Acid phosphatase 1, isoform b.
Suggested positive control: antigen standard for ACP1 (transient overexpression lysate), human liver protein, liver lysate.
ACP1 is a unique member of Phosphotyrosine Protein phosphotase family of proteins. It is ubiquitously expressed acid phosphotase functioning as an acid phosphotase and a protein tyrosine phosphotase. ACP1 has a cysteine-based catalytic mechanism and hydrolyzes protein tyrosine phosphate to protein tyrosine and orthophosphate. Reports suggest a functional role of ACP1 in TCR signaling and control of cell-cell adhesion through regulation of cytoskeletion assembly.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.