|Tested species reactivity||Bovine, Dog, Fish, Guinea pig, Goat, Hamster, Human, Mouse, Sheep, Pig, Rabbit, Rat, Xenopus|
|Host / Isotype||Mouse / IgG2a|
|Immunogen||Synthetic peptide: SGPSIVHRKCF (human) attached to a Multiple Antigen Peptide (MAP) backbone|
|Storage buffer||PBS, pH 7.4, with 1% BSA|
|Contains||15mM sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Immunohistochemistry (Frozen) (IHC (F))||Assay Dependent|
|Immunohistochemistry (Paraffin) (IHC (P))||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA1-24908 detects Actin from human, mouse, rat, Xenopus laevis, bovine, carp, canine, goat, guinea pig, hamster, porcine, rabbit, and ovine samples.
MA1-24908 has been successfully used in immunofluorescence, immunohistochemistry (frozen and paraffin) procedures.
The MA1-24908 immunogen is a synthetic peptide corresponding to the C-terminal residues S G P S I V H R K C F of human Actin attached to a Multiple Antigen Peptide (MAP) backbone.
The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.