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|Tested species reactivity||Dog, Chicken, Cat, Human, Mouse, Primate, Rabbit, Rat|
|Published species reactivity||Human, Mouse|
|Host / Isotype||Mouse / IgG1|
|Immunogen||SDS extracted protein fraction of human myocardium|
|Storage buffer||PBS, pH 7.4|
|Contains||15mM sodium azide|
|Storage Conditions||4° C, do not freeze|
|Tested Applications||Dilution *|
|Immunohistochemistry (Frozen) (IHC (F))||Assay Dependent|
|Immunohistochemistry (Paraffin) (IHC (P))||Assay Dependent|
|Western Blot (WB)||1 ug/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This antibody recognizes muscle-specific alpha and gamma actin (42 kDa) in various species. This antibody stains skeletal, smooth and myocardial cells as well as myoepithelial cells and pericytes of small vessels. It is a widely used marker of muscle and muscle-derived cells.
Actin is a highly conserved ubiquitous globular protein (G-actin) that polymerizes to form fibrous F-actin microfilaments. In higher eucaryotes several actin isoforms have been identified, that fall into three classes. Alpha actin is a structural component of the contractile apparatus of muscle cells or muscle-derived cells. beta actin and gamma actin play roles in regulation of cell motility in other cell types. Specific subcellular structures such as as stress fibers, focal adhesions, filopodia etc., are formed by involvement of actin cytoskeleton.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Plexiform fibromyxoma (plexiform angiomyxoid myofibroblastic tumor) of stomach: an unusual presentation as a fistulating abscess.
MA1-10046 was used in immunohistochemistry to report on a case of plexiform fibromyxoma of the stomach
|Lee PW,Yau DT,Lau PP,Chan JK||International journal of surgical pathology (22:286)||2014|
Expression of E-cadherin in angiomyolipoma.
MA1-10046 was used in immunohistochemistry to perform a systematic study of E-cadherin expression in angiomyolipoma
|Wang Z,Gong Q,Fan Q||Human pathology (43:2348)||2012|
Sporadic haemangioblastoma of the kidney with rhabdoid features and focal CD10 expression: report of a case and literature review.
MA1-10046 was used in immunohistochemistry to report on a case of sporadic haemangioblastoma of the kidney with rhabdoid features and focal CD10 expression
|Yin WH,Li J,Chan JK||Diagnostic pathology (7:null)||2012|
Tumor-in-tumor of the thyroid with basaloid differentiation: a lesion with a solid cell nest neoplastic component?
MA1-10046 was used in immunohistochemistry to report on a case of tumor-in-tumor of the thyroid with basaloid differentiation
|Eloy C,Vinagre J,Cameselle-Teijeiro J,Paiva ME,Soares P,Sobrinho-Simões M||International journal of surgical pathology (19:276)||2011|
Chorangiosis: the potential role of smoking and air pollution.
MA1-10046 was used in immunohistochemistry to investigate the role of smoking and air pollution in the development of chorangiosis
|Akbulut M,Sorkun HC,Bir F,Eralp A,Duzcan E||Pathology, research and practice (205:75)||2009|
Myointimoma of the glans penis.
MA1-10046 was used in immunohistochemistry to report on a case of myointimoma of the glans penis
|Vardar E,Gunlusoy B,Arslan M,Kececi S||Pathology international (57:158)||2007|
Ectopic cervical anaplastic ependymoma.
MA1-10046 was used in immunohistochemistry to report on a case of ectopic cervical anaplastic ependymoma
|Wang Z,Huang G,Yan P,Liang R,Wang J,Yan Q,Zhang J,Cheng H,Hu P,Ma MJ||Pathology international (55:781)||2005|
Cutaneous lymphoid hyperplasia and other lymphoid infiltrates of the breast nipple: a retrospective clinicopathologic study of fifty-six patients.
MA1-10046 was used in immunohistochemistry to study the clinicopathological spectrum of lymphoproliferations and other lymphoid infiltration of the breast nipple
|Boudova L,Kazakov DV,Sima R,Vanecek T,Torlakovic E,Lamovec J,Kutzner H,Szepe P,Plank L,Bouda J,Hes O,Mukensnabl P,Michal M||The American Journal of dermatopathology (27:375)||2005|
Epstein-Barr virus-associated smooth muscle tumour: a distinctive mesenchymal tumour of immunocompromised individuals.
MA1-10046 was used in immunohistochemistry to report on a case of Epstein-Barr virus-associated smooth muscle tumour
|Cheuk W,Li PC,Chan JK||Pathology (34:245)||2002|
G-CSF promotes the proliferation of developing cardiomyocytes in vivo and in derivation from ESCs and iPSCs.
MA1-10046 was used in immunocytochemistry to investigate the expression level of G-CSFR in vivo and the role of G-CSF during cardiomyogenesis in vitro and in vivo
|Shimoji K,Yuasa S,Onizuka T,Hattori F,Tanaka T,Hara M,Ohno Y,Chen H,Egasgira T,Seki T,Yae K,Koshimizu U,Ogawa S,Fukuda K||Cell stem cell (6:227)||2010|
Microfabrication-based modulation of embryonic stem cell differentiation.
MA1-10046 was used in immunocytochemistry to study the effect of microfabricated adhesive stencils on embryonic stem cell differentiation
|Park J,Cho CH,Parashurama N,Li Y,Berthiaume F,Toner M,Tilles AW,Yarmush ML||Lab on a chip (7:1018)||2007|
a-actin; ACTA; actin; actin alpha 1; actin alpha cardiac; actin alpha cardiac 1; actin, alpha cardiac muscle 1; actin, alpha skeletal muscle; actin, alpha, cardiac 1; actin, alpha, cardiac muscle 1; actin, alpha, vascular smooth muscle; actin, aortic smooth muscle; actin, cytoplasmic 2; actin, gamma, cytoplasmic 1; alpha skeletal muscle; alpha skeletal muscle actin; alpha-actin; alpha-actin cardiac; alpha-actin-1; alpha-actin-2; alpha-cardiac actin; alpha-sma; alpha-smooth muscle actin; alphac-actin; ASMA; beta-actin FE-3; cardiac actin; cell growth-inhibiting gene 46 protein; CFTD; CFTD1; CFTDM; cytoskeletal gamma-actin; deafness, autosomal dominant 20; deafness, autosomal dominant 26; epididymis luminal protein 176; gamma-actin; MPFD; NEM1; NEM2; NEM3; nemaline myopathy type 3; RP5-1068B5.2; smooth muscle alpha-actin
0610041G09Rik; a-SMA; AA959943; AAT6; ACT; ACTA; Acta-2; ACTA1; ACTA2; ACTC; Actc-1; ACTC1; ACTG; ACTG1; Actl; Acts; ACTSA; Actsk-1; ACTVS; AL023024; alphaSMA; ASD5; ASMA; BRWS2; CFTD; CFTD1; CFTDM; CMD1R; CMH11; DFNA20; DFNA26; E51; GIG46; HEL-176; LVNC4; MPFD; MYMY5; NEM1; NEM2; NEM3; SHPM; SMalphaA
(Human) P68133, (Chicken) P68139, (Human) P62736, (Rabbit) P62740, (Chicken) P08023, (Human) P04270, (Chicken) P68034, (Human) P63261, (Rat) P68136, (Mouse) P68134, (Rat) P62738, (Mouse) P62737, (Mouse) P68033, (Rat) P68035, (Mouse) P63260, (Rat) P63259
(Human) 58, (Chicken) 421534, (Human) 59, (Rabbit) 100009271, (Chicken) 423787, (Human) 70, (Rabbit) 100340339, (Dog) 478250, (Chicken) 423298, (Human) 71, (Rat) 29437, (Mouse) 11459, (Rat) 81633, (Mouse) 11475, (Mouse) 11464, (Rat) 29275, (Mouse) 11465, (Rat) 287876