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|Tested species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 38-67 amino acids from the N-terminal region of human Actin (ACTB/ACTC)|
|Purification||Size-exclusion - Dialysis, Ammonium sulfate precipitation|
|Contains||0.09% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:10-1:50|
|Western Blot (WB)||1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This antibody is predicted to react with bovine, chicken, canine, equine, hamster, porcine, non-human primate, rat, rabbit and Xenopus, yeast and zebrafish based on sequence homology.
Actins are highly conserved proteins that are involved in cell motility, structure, and integrity. ACTB/ACTC are nonmuscle cytoskeletal actins and major constituents of the contractile apparatus. Defects in ACTB are a cause of juvenile-onset dystonia. Defects in ACTC have been associated with idiopathic dilated cardiomyopathy (IDC) and familial hypertrophic cardiomyopathy (FHC).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
ACTC1; actin alpha cardiac; actin, alpha cardiac muscle 1; actin, beta; alpha-cardiac actin; alphac-actin; Atcb; beta cytoskeletal actin; PS1TP5-binding protein 1
ACTB; ACTC; Actc-1; ACTC1; ASD5; BRWS1; CMD1R; CMH11; LVNC4; PS1TP5BP1