This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details
This antibody recognizes muscle-specific alpha and gamma actin (42 kDa) in various species. This antibody stains skeletal, smooth and myocardial cells as well as myoepithelial cells and pericytes of small vessels. It is a widely used marker of muscle and muscle-derived cells.
Actin is a highly conserved ubiquitous globular protein (G-actin) that polymerizes to form fibrous F-actin microfilaments. In higher eucaryotes several actin isoforms have been identified, that fall into three classes. Alpha actin is a structural component of the contractile apparatus of muscle cells or muscle-derived cells. beta actin and gamma actin play roles in regulation of cell motility in other cell types. Specific subcellular structures such as as stress fibers, focal adhesions, filopodia etc., are formed by involvement of actin cytoskeleton.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: a-actin; ACTA; actin; actin alpha 1; actin alpha cardiac; actin alpha cardiac 1; actin, alpha 1, skeletal muscle; Actin, alpha cardiac muscle 1; Actin, alpha cardiac muscle 1, intermediate form; Actin, alpha skeletal muscle; Actin, alpha skeletal muscle, intermediate form; actin, alpha, cardiac 1; actin, alpha, cardiac muscle 1; actin, alpha, vascular smooth muscle; Actin, aortic smooth muscle; Actin, aortic smooth muscle, intermediate form; Actin, cytoplasmic 2; Actin, cytoplasmic 2, N-terminally processed; Actin, cytoplasmic type 5; actin, cytoplasmic, type 5; actin, gamma 1; actin, gamma 1 propeptide; actin, gamma, cytoplasmic 1; alpha skeletal muscle; alpha skeletal muscle actin; Alpha-actin; alpha-actin cardiac; Alpha-actin-1; Alpha-actin-2; Alpha-cardiac actin; alpha-sma; alpha-smooth muscle actin; alphac-actin; ASMA; beta-actin FE-3; cardiac actin; Cell growth-inhibiting gene 46 protein; CFTD; CFTD1; CFTDM; cytoplasmic 2; cytoplasmic beta-actin; cytoplasmic type 5; cytoskeletal gamma-actin; deafness, autosomal dominant 20; deafness, autosomal dominant 26; epididymis luminal protein 176; gamma 1 propeptide; Gamma-actin; MPFD; NEM1; NEM2; NEM3; nemaline myopathy type 3; RP5-1068B5.2; smooth muscle alpha-actin; type 5
Gene Aliases: 0610041G09Rik; a-SMA; AA959943; AAT6; ACT; ACTA; Acta-2; ACTA1; ACTA2; ACTC; Actc-1; ACTC1; ACTG; ACTG1; actin; Actl; Acts; ACTSA; Actsk-1; ACTVS; AL023024; alphaSMA; ASD5; ASMA; BRWS2; CFTD; CFTD1; CFTDM; CMD1R; CMH11; cytoplasmic; DFNA20; DFNA26; E51; GIG46; HEL-176; LVNC4; MPFD; MYMY5; NEM1; NEM2; NEM3; RCJMB04_1h13; SHPM; SMalphaA
UniProt ID: (Chicken) P68139, (Human) P68133, (Rabbit) P62740, (Chicken) P08023, (Human) P62736, (Human) P68032, (Chicken) P68034, (Human) P63261, (Chicken) P53478, (Mouse) P68134, (Rat) P68136, (Rat) P62738, (Mouse) P03996, (Mouse) P68033, (Rat) P68035, (Mouse) P63260, (Rat) P63259
Entrez Gene ID: (Chicken) 421534, (Human) 58, (Dog) 488984, (Rabbit) 100009271, (Chicken) 423787, (Human) 59, (Dog) 477587, (Cat) 100144392, (Human) 70, (Dog) 478250, (Chicken) 423298, (Rabbit) 100340339, (Human) 71, (Chicken) 415296, (Dog) 475923, (Mouse) 11459, (Rat) 29437, (Rat) 81633, (Mouse) 11475, (Mouse) 11464, (Rat) 29275, (Mouse) 11465, (Rat) 287876, (Rabbit) 100009506