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|Tested species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to a region within amino acids 441 and 503 of Human Activin A Receptor Type II-like 1|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 1% BSA, 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:1000-1:10,000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-27081 targets Activin A Receptor Type II-like 1 in IHC (P) and WB applications and shows reactivity with Human and mouse samples.
The PA5-27081 immunogen is synthetic peptide corresponding to a region within amino acids 441 and 503 of Human Activin A Receptor Type II-like 1.
This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
activin A receptor; activin A receptor type II-like 1; activin A receptor type IL; activin A receptor, type II-like kinase 1; activin receptor-like kinase 1; activin receptor-like kinase-1; ACVRLK1; ALK-1; ALK1; HHT; HHT2; ORW2; serine/threonine-protein kinase receptor R3; SKR3; TGF-B superfamily receptor type I; TSR-I; type II-like kinase 1
ACVRL1; ACVRLK1; AI115505; AI427544; ALK-1; ALK1; HHT; HHT2; ORW2; SKR3; TSR-I