This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details
Immunogen sequence: QVELHVHLDG SIKPETILYY GRRRGIALPA NTAEGLLNVI GMDKPLTLPD FLAKFDYYMP AIAGCREAIK RIAYEFVEMK AKEGVVYVEV RYSPHLLANS KVEPIPWNQA EGDLTPDEVV ALVGQGLQEG ERDFGVKARS ILCC
Highest antigen sequence identity to the following orthologs: Mouse - 83%, Rat - 88%.
Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. Acts as a positive regulator of T-cell coactivation, by binding DPP4. Its interaction with DPP4 regulates lymphocyte-epithelial cell adhesion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ADAR1; Adenosine aminohydrolase; Adenosine deaminase; adenosine deaminase acting on RNA 1-A; double-stranded RNA-specific adenosine deaminase; DSH; DSRAD; G1P1; IFI4; interferon-induced protein 4; interferon-inducible protein 4; P136; RP11-61L14.5
Gene Aliases: ADA; ADA1
UniProt ID: (Human) P00813
Entrez Gene ID: (Human) 100