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Invitrogen
Adenosine Deaminase Polyclonal Antibody
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FIGURE: 1 / 3
Adenosine Deaminase Antibody (PA5-80315) in ICC/IF
Immunofluorescence staining of Adenosine Deaminase in A549 cells. Cells were fixed with 4% PFA, blocked with 10% serum, and incubated with Adenosine Deaminase Polyclonal Antibody (Product # PA5-80315, 1:1,000) at 4°C overnight. Then cells were stained with the Alexa Fluor®594-conjugated Goat Anti-rabbit IgG secondary antibody (red) and counterstained with DAPI (blue). Positive staining was localized to cyto... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-80315
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to the C-terminus of the Human ADA/Adenosine deaminase
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A, Antigen affinity chromatography
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
This antibody has specificity for Human ADA/Adenosine deaminase.
Target Information
Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. May act as a positive regulator of T-cell coactivation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: adenosine aminohydrolase; RP11-61L14.5
Gene Aliases: ADA1
UniProt ID: (Human) P00813
Entrez Gene ID: (Human) 100
response to hypoxia
adenosine catabolic process
AMP catabolic process
xenobiotic metabolic process
purine ribonucleoside monophosphate biosynthetic process
response to purine-containing compound
purine nucleotide salvage
GMP salvage
regulation of cell-cell adhesion mediated by integrin
T cell activation
purine-containing compound salvage
hypoxanthine salvage
AMP salvage
regulation of circadian sleep/wake cycle, sleep
dAMP catabolic process
adenosine metabolic process
inosine biosynthetic process
negative regulation of adenosine receptor signaling pathway
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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