Human ADA shares 82.5% and 82.9% amino acid (aa) sequence identity with mouse and rat ADA, respectively.
Reconstitution information: Add 0.2 mL of distilled water will yield a concentration of 500 µg/mL.
Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. May act as a positive regulator of T-cell coactivation.
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Protein Aliases: Adenosine aminohydrolase; Adenosine deaminase
Gene Aliases: ADA; ADA1
UniProt ID: (Human) P00813
Entrez Gene ID: (Human) 100