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Invitrogen
Adenylate Kinase 1 Polyclonal Antibody
Product Details
PA5-52297
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human Adenylate Kinase 1. Recombinant protein control fragment (Product #RP-101070).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2637699
Product Specific Information
Immunogen sequence: EKGQLVPLET VLDMLRDAMV AKVNTSKGFL IDGYPREVQQ GEEFERRIGQ PTLLLYVDAG PETMTQRLLK RGETSGRVDD NEETIKKRLE TYYKATEPVI AFYEKRGIVR KVNAEGS
Highest antigen sequence identity to the following orthologs: Mouse - 88%, Rat - 69%.
Target Information
Adenylate kinase is an enzyme involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate group among adinine nucleotides. Three isozymes of adenylate kinase have been identified in vertebrates, adenylate isozyme 1 (AK1), 2 (AK2) and 3 (AK3). AK1 is found in the cytosol of skeletal muscle, brain and erythrocytes, whereas AK2 and AK3 are found in the mitochondria of other tissues including liver and heart. AK1 was identified because of its association with a rare genetic disorder causing nonspherocytic hemolytic anemia where a mutation in the AK1 gene was found to reduce the catalytic activity of the enzyme.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Adenylate kinase isoenzyme 1; adenylate kinase isoenzyme 1 {ECO:0000255|HAMAP-Rule:MF_03171}; Adenylate monophosphate kinase; adenylate monophosphate kinase {ECO:0000255|HAMAP-Rule:MF_03171}; AK 1; AK 1 {ECO:0000255|HAMAP-Rule:MF_03171}; ATP-AMP transphosphorylase 1; ATP-AMP transphosphorylase 1 {ECO:0000255|HAMAP-Rule:MF_03171}; ATP:AMP phosphotransferase; ATP:AMP phosphotransferase {ECO:0000255|HAMAP-Rule:MF_03171}; cytosolic adenylate kinase; Myokinase; myokinase {ECO:0000255|HAMAP-Rule:MF_03171}; testis secretory sperm binding protein Li 58j
Gene Aliases: Ak 1; Ak-1; AK1; B430205N08Rik; HTL-S-58j
UniProt ID: (Human) P00568, (Mouse) Q9R0Y5, (Rat) P39069
Entrez Gene ID: (Human) 203, (Mouse) 11636, (Rat) 24183
nucleoside diphosphate phosphorylation
ADP biosynthetic process
cell cycle arrest
nucleoside triphosphate biosynthetic process
nucleobase-containing small molecule interconversion
AMP metabolic process
ATP metabolic process
nucleobase-containing compound metabolic process
positive regulation of glucose transport
phosphorylation
inosine biosynthetic process
nucleotide phosphorylation
muscle organ development
positive regulation of neuron maturation
response to activity
cerebellum development
olfactory bulb development
neuron differentiation
response to estradiol
response to testosterone
response to drug
adenine metabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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