Adenylate kinases are involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. Five isozymes of adenylate kinase have been identified in vertebrates. Expression of these isozymes is tissue-specific and developmentally regulated. Isozyme 2 is localized in the mitochondrial intermembrane space and may play a role in apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 2743; Adenylate kinase 2; Adenylate kinase 2, mitochondrial; Adenylate kinase 2, mitochondrial, N-terminally processed; adenylate kinase isoenzyme 2, mitochondrial; Adenylate monophosphate kinase; AK 2; ak2; ATP-AMP transphosphorylase 2; ATP:AMP phosphotransferase; mitochondrial; testis secretory sperm-binding protein Li 220n
Gene Aliases: ADK2; Ak-2; AK2; D4Ertd220e; si:ch211-197n10.1; wu:fb34f05; wu:fj80e03