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Invitrogen
Adenylate Kinase 2 Recombinant Rabbit Monoclonal Antibody (JE64-27)
FIGURE: 1 / 3
Adenylate Kinase 2 Antibody (MA5-44760) in IHC (P)
Immunohistochemistry analysis of AK2 in paraffin-embedded human kidney tissue. The section was pre-treated using heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0) for 20 minutes. The tissues were blocked in 1% BSA for 20 minutes at room temperature, washed with ddH2O and PBS, and then probed with AK2 Monoclonal antibody (Product # MA5-44760) using a dilution of 1:100 for 1 hour at room temperat... View More
Product Details
MA5-44760
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
JE64-27
Immunogen
Synthetic peptide within human AK2 aa 150-200/239.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
TBS, pH 7.4, with 40% glycerol, 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2931218
Target Information
Adenylate kinases are involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. Three isozymes of adenylate kinase, namely 1, 2, and 3, have been identified in vertebrates; this gene encodes isozyme 2. Expression of these isozymes is tissue-specific and developmentally regulated. Isozyme 2 is localized in the mitochondrial intermembrane space and may play a role in apoptosis. Two transcript variants encoding distinct isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Adenylate kinase 2, mitochondrial; adenylate kinase 2, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03168}; adenylate kinase isoenzyme 2, mitochondrial; Adenylate monophosphate kinase; adenylate monophosphate kinase {ECO:0000255|HAMAP-Rule:MF_03168}; AK 2; AK 2 {ECO:0000255|HAMAP-Rule:MF_03168}; ATP-AMP transphosphorylase 2; ATP-AMP transphosphorylase 2 {ECO:0000255|HAMAP-Rule:MF_03168}; ATP:AMP phosphotransferase; ATP:AMP phosphotransferase {ECO:0000255|HAMAP-Rule:MF_03168}; testis secretory sperm-binding protein Li 220n
Gene Aliases: ADK2; Ak-2; AK2; D4Ertd220e
UniProt ID: (Human) Q8TCY2, (Rat) P29410, (Mouse) Q9WTP6
Entrez Gene ID: (Human) 204, (Rat) 24184, (Mouse) 11637
liver development
oxidative phosphorylation
ADP biosynthetic process
brain development
nucleobase-containing small molecule interconversion
AMP metabolic process
dATP metabolic process
nucleotide phosphorylation
response to thyroid hormone
ATP metabolic process
adenine metabolic process
nucleobase-containing compound metabolic process
phosphorylation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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