Recommended positive controls: HeLa.
Predicted reactivity: Mouse (87%), Rat (88%), Bovine (89%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The adenylate kinases (AK) are a family of structurally and functionally related enzymes that catalyze a similar reaction, MgNTP + AMP = MgNDP + ADP (N = A or G). The AK enzymes are important for maintenance of homeostasis of the adenine and guanine nucleotide pools. AK1 is a cytosolic enzyme for which ATP is the substrate. AK2 catalyzes the same reaction as AK1, but it is localized in the mitochondrial intermembrane space. AK3 is present in the mitochondrial matrix and prefers GTP over ATP as the substrate.
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Protein Aliases: Adenylate kinase 7; AK 7; ATP-AMP transphosphorylase 7; putative adenylate kinase 7
Gene Aliases: AK 7; AK7
UniProt ID: (Human) Q96M32
Entrez Gene ID: (Human) 122481
Molecular Function: nucleotide kinase