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|Tested species reactivity||Human, Rat|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Purified, full length, native ACTH, conjugated to BSA.|
|Contains||10mM sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|ELISA (ELISA)||Assay Dependent|
|Immunocytochemistry (ICC)||Assay Dependent|
|Immunohistochemistry (Paraffin) (IHC (P))||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA1-27354 detects ACTH from human and rat samples.
MA1-27354 has been successfully used in immunocytochemistry, and immunohistochemistry (FFPE) procedures.
The MA1-27354 immunogen is purified, full length, native ACTH, conjugated to BSA. The epitope is contained within the C-terminal region, as the antibody specifically detects CLIP (ACTH 17-39) but does not cross-react with Synacthen (ACTH 1-24).
Human adrenocorticotrophin (ACTH) is a 39 amino acid cleavage product from pro-opiomelanocortin (POMC) which elicits a classic glucocorticoid response from the adrenal glands in situations of stress. ACTH is produced in the pituitary, and also by lymphocytes and macrophages.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Adrenocorticotropic Hormone; adrenocorticotropin; alpha-melanocyte-stimulating hormone; alpha-MSH; beta-endorphin; beta-LPH; beta-melanocyte-stimulating hormone; beta-MSH; corticotropin-like intermediary peptide; corticotropin-lipotropin; gamma-LPH; gamma-MSH; lipotropin beta; lipotropin gamma; melanotropin alpha; melanotropin beta; melanotropin gamma; met-enkephalin; opiomelanocortin prepropeptide; pro-ACTH-endorphin; pro-opiomelanocortin; pro-opiomelanocortin-alpha; proopiomelanocortin (adrenocorticotropin/ beta-lipotropin/ alpha-melanocyte stimulating hormone/ beta-melanocyte stimulating hormone/ beta-endorphin); proopiomelanocortin preproprotein; proopiomelanocortin, beta (endorphin, beta); proopoimelanocortin, beta (endorphin, beta)
ACTH; alphaMSH; CLIP; LPH; MSH; NPP; POC; POMC; Pomc1; Pomc2