Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
Immunogen sequence: ADTARLDVAS EFRKKWNKWA LSRGKRELRM SSSYPTGLAD VKAGPAQTLI RPQDMKGASR S
Adrenomedullin (ADM), a vasodilator produced by most contractile cells, is characterized by persistent hypotensive activity. ADM is involved in the regulation of fluid and electrolyte homeostasis and in the maintenance of cardiovascular functioning. In hypertensive patients, the level of ADM in plasma is upregulated. Natriuresis is a common systemic manifestation of aneurysmal subarachnoid hemorrhage. ADM has strong natriuretic actions. ADM-induced natriuresis is caused by an increase in glomerular filtration rate and a decrease in distal tubular sodium reabsorption. ADM is present both in the periphery and brain, and can exert central effects such as decreasing food ingestion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: AMpreproadrenomedullin; preproadrenomedullin; Pro-adrenomedullin; proadrenomedullin N-20 terminal peptide; ProAM-N20
Gene Aliases: ADM; AM; PAMP
UniProt ID: (Human) P35318
Entrez Gene ID: (Human) 133
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