|Tested species reactivity||Chemical|
|Host / Isotype||Mouse / IgG1, kappa|
|Immunogen||Aflatoxin B1 DNA (against the imidazole ring-opened persistent form of the major N-7 guanine adduct of AFB1).|
|Contains||0.1% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|ELISA (ELISA)||5 µg/ml|
|Immunohistochemistry (Frozen) (IHC (F))||Assay-Dependent|
|Immunohistochemistry (Paraffin) (IHC (P))||Assay-Dependent|
|Western Blot (WB)||1:500-1:2000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This antibody does not cross-react with other carcinogen-DNA adducts.
Suggested positive control: human HepG2 liver samples.
Aflatoxin is a naturally occurring mycotoxin produced by two types of mold: Aspergillus flavus and Aspergillus parasiticus. Aspergillus flavus is common and widespread in nature and is most often found when certain grains are grown under stressful conditions such as drought. At least 13 different types of aflatoxin are produced in nature with aflatoxin B1 considered as the most toxic. Aflatoxin B1 exposure may be a potential etiological agent in hepatocellular carcinoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.