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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 8 and 203 of Akirin 2 (Uniprot ID#Q53H80)|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:5000-1:20,000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-34875 targets Akirin 2 in WB applications and shows reactivity with Human samples.
The PA5-34875 immunogen is recombinant fragment corresponding to a region within amino acids 8 and 203 of Akirin 2 (Uniprot ID#Q53H80).
Required for the innate immune response. Downstream effector of the Toll-like receptor (TLR), TNF and IL-1 beta signaling pathways leading to the production of IL-6. Forms a complex with YWHAB that acts to repress transcription of DUSP1 .
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
14-3-3 beta; akirin-2; C6orf166; dJ486L4.2; FBI1; fourteen-three-three beta interactant 1
AKIRIN2; C6orf166; dJ486L4.2; FBI1