|Western Blot (WB)||1:5000|
|Tested Species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant contstruct containing the 7th, 8th, 9th repeats of human alpha II spectrin|
|Contains||10mM sodium azide|
This antibody contains enough material to conduct 10 mini-Western blots.
Spectrins are a family of filamentous cytoskeletal proteins that function as essential scaffold proteins that stabilize the plasma membrane and organize intracellular organelles. Spectrins are composed of alpha and beta dimers that associate to form tetramers linked in a head-to-head arrangement. This gene encodes an alpha spectrin that is specifically expressed in nonerythrocytic cells. The encoded protein has been implicated in other cellular functions including DNA repair and cell cycle regulation. Mutations in this gene are the cause of early infantile epileptic encephalopathy-5. Alternate splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: a--fodrin; alpha II spectrin; alpha-fodrin; Alpha-II spectrin; alpha-spectrin 2; alpha-spectrin 2, brain; brain alpha-spectrin; Fodrin alpha chain; inhibitory protein factor; noerythroid alpha-spectrin 2; nonerythroid alpha-spectrin 2; spectrin alpha chain, brain; Spectrin alpha chain, non-erythrocytic 1; spectrin, non-erythroid alpha chain; Spectrin, non-erythroid alpha subunit
Gene Aliases: 2610027H02Rik; A2a; EIEE5; IPF; NEAS; Spna-2; Spna2; SPTA2; SPTAN1
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.