Product References
miR-135a Alleviates Silica-Induced Pulmonary Fibrosis by Targeting NF-κB/Inflammatory Signaling Pathway.
Mediators of inflammation
Xie B,Lu C,Chen C,Zhou J,Deng Z
14-9760 was used in Immunohistochemistry-immunofluorescence to investigate the roles and mechanisms of miR-135a underlying silica-induced pulmonary fibrosis.
Mon Jun 07 00:00:00 EDT 2021
Leflunomide Induces Dose-Dependent Lung Injury in Mice via Stimulating Vimentin and NLRP3 Inflammasome Production.
Frontiers in pharmacology
El-Sherbiny M,Atef H,Eladl MA,Mohamed AS,El-Shafey M,Ali HS,Zaitone SA,Alomar SY,Alqahtani SAM,Aloyouni SY,Attia MA
14-9760-82 was used in Western Blot to examine the dose-dependent lung injury produced by leflunomide in healthy mice.
Tue May 18 00:00:00 EDT 2021
Leflunomide Induces Dose-Dependent Lung Injury in Mice via Stimulating Vimentin and NLRP3 Inflammasome Production.
Frontiers in pharmacology
El-Sherbiny M,Atef H,Eladl MA,Mohamed AS,El-Shafey M,Ali HS,Zaitone SA,Alomar SY,Alqahtani SAM,Aloyouni SY,Attia MA
14-9760-82 was used in Western Blot to examine the dose-dependent lung injury produced by leflunomide in healthy mice.
Tue May 18 00:00:00 EDT 2021
Knockout RAGE alleviates cardiac fibrosis through repressing endothelial-to-mesenchymal transition (EndMT) mediated by autophagy.
Cell death & disease
Zhang L,He J,Wang J,Liu J,Chen Z,Deng B,Wei L,Wu H,Liang B,Li H,Huang Y,Lu L,Yang Z,Xian S,Wang L
Published figure using Alpha-Smooth Muscle Actin monoclonal antibody (Product # 14-9760-82) in Flow Cytometry
Tue May 11 00:00:00 EDT 2021
Knockout RAGE alleviates cardiac fibrosis through repressing endothelial-to-mesenchymal transition (EndMT) mediated by autophagy.
Cell death & disease
Zhang L,He J,Wang J,Liu J,Chen Z,Deng B,Wei L,Wu H,Liang B,Li H,Huang Y,Lu L,Yang Z,Xian S,Wang L
Published figure using Alpha-Smooth Muscle Actin monoclonal antibody (Product # 14-9760-82) in Flow Cytometry
Tue May 11 00:00:00 EDT 2021
A multilayered scaffold for regeneration of smooth muscle and connective tissue layers.
Journal of biomedical materials research. Part A
Garrison CM,Singh-Varma A,Pastino AK,Steele JAM,Kohn J,Murthy NS,Schwarzbauer JE
14-9760-82 was used in Immunocytochemistry to demonstrate if differently-oriented scaffold fibers direct cell and extracellular matrix (ECM) organisation, and if scaffold fibers and extracellular matrix protein networks are maintained after decellularization.
Sat May 01 00:00:00 EDT 2021
Fibroblastic reticular cell lineage convergence in Peyer's patches governs intestinal immunity.
Nature immunology
Prados A,Onder L,Cheng HW,Mörbe U,Lütge M,Gil-Cruz C,Perez-Shibayama C,Koliaraki V,Ludewig B,Kollias G
Published figure using Alpha-Smooth Muscle Actin monoclonal antibody (Product # 14-9760-82) in Flow Cytometry
Thu Apr 01 00:00:00 EDT 2021
Gut-liver axis modulation of Panax notoginseng saponins in nonalcoholic fatty liver disease.
Hepatology international
Xu Y,Wang N,Tan HY,Li S,Zhang C,Feng Y
Published figure using Alpha-Smooth Muscle Actin monoclonal antibody (Product # 14-9760-82) in Immunohistochemistry
Thu Apr 01 00:00:00 EDT 2021
Two novel TSC2 mutations in renal epithelioid angiomyolipoma sensitive to everolimus.
Cancer biology & therapy
Wang T,Xie S,Luo R,Shi L,Bai P,Wang X,Wan R,Deng J,Wu Z,Li W,Xiao W,Wang Y,Chen B,Zhang K,Xing J
Published figure using Alpha-Smooth Muscle Actin monoclonal antibody (Product # 14-9760-82) in Immunohistochemistry
Mon Mar 29 00:00:00 EDT 2021
Two novel TSC2 mutations in renal epithelioid angiomyolipoma sensitive to everolimus.
Cancer biology & therapy
Wang T,Xie S,Luo R,Shi L,Bai P,Wang X,Wan R,Deng J,Wu Z,Li W,Xiao W,Wang Y,Chen B,Zhang K,Xing J
Published figure using Alpha-Smooth Muscle Actin monoclonal antibody (Product # 14-9760-82) in Immunohistochemistry
Mon Mar 29 00:00:00 EDT 2021
The KLB rs17618244 gene variant is associated with fibrosing MAFLD by promoting hepatic stellate cell activation.
EBioMedicine
Panera N,Meroni M,Longo M,Crudele A,Valenti L,Bellacchio E,Miele L,D'Oria V,Paolini E,Maggioni M,Fracanzani AL,Alisi A,Dongiovanni P
14-9760-82 was used in Immunocytochemistry to reveal a signaling pathway wherein leptin modulates NMDARs via Src to regulate β-cell excitability and suggests NMDARs as a potential target to overcome leptin resistance.
Mon Mar 01 00:00:00 EST 2021
The β-catenin/YAP signaling axis is a key regulator of melanoma-associated fibroblasts.
Signal transduction and targeted therapy
Liu T,Zhou L,Yang K,Iwasawa K,Kadekaro AL,Takebe T,Andl T,Zhang Y
14-9760-82 was used in Immunohistochemistry to provide a new paradigm in which the β-catenin-YAP signaling axis regulates the activation and tumor-promoting function of stromal fibroblasts.
Fri Jan 29 00:00:00 EST 2021
The β-catenin/YAP signaling axis is a key regulator of melanoma-associated fibroblasts.
Signal transduction and targeted therapy
Liu T,Zhou L,Yang K,Iwasawa K,Kadekaro AL,Takebe T,Andl T,Zhang Y
14-9760-82 was used in Immunohistochemistry to provide a new paradigm in which the β-catenin-YAP signaling axis regulates the activation and tumor-promoting function of stromal fibroblasts.
Fri Jan 29 00:00:00 EST 2021
Maintaining resting cardiac fibroblasts in vitro by disrupting mechanotransduction.
PloS one
Gilles G,McCulloch AD,Brakebusch CH,Herum KM
14-9760 was used in Immunocytochemistry-immunoflourescence to investigate the extent to which disrupting mechanotransduction by culturing cardiac fibroblasts on soft hydrogels or in the presence of biochemical inhibitors can be used to maintain resting cardiac fibroblasts in vitro.
Mon Dec 21 00:00:00 EST 2020
Maintaining resting cardiac fibroblasts in vitro by disrupting mechanotransduction.
PloS one
Gilles G,McCulloch AD,Brakebusch CH,Herum KM
14-9760 was used in Immunocytochemistry-immunoflourescence to investigate the extent to which disrupting mechanotransduction by culturing cardiac fibroblasts on soft hydrogels or in the presence of biochemical inhibitors can be used to maintain resting cardiac fibroblasts in vitro.
Mon Dec 21 00:00:00 EST 2020
Smooth muscle-derived progenitor cell myofibroblast differentiation through KLF4 downregulation promotes arterial remodeling and fibrosis.
JCI insight
Lu S,Jolly AJ,Strand KA,Dubner AM,Mutryn MF,Moulton KS,Nemenoff RA,Majesky MW,Weiser-Evans MC
Published figure using Alpha-Smooth Muscle Actin monoclonal antibody (Product # 14-9760-82) in Flow Cytometry
Thu Dec 03 00:00:00 EST 2020
Platelet polyphosphate induces fibroblast chemotaxis and myofibroblast differentiation.
Journal of thrombosis and haemostasis : JTH
Suess PM,Smith SA,Morrissey JH
Published figure using Alpha-Smooth Muscle Actin monoclonal antibody (Product # 14-9760-82) in Immunocytochemistry
Sun Nov 01 00:00:00 EDT 2020
Hyperion imaging system reveals heterogeneous tumor microenvironment of oral squamous cell carcinoma patients at T1N0M0 stage.
Annals of translational medicine
Xie S,Shan XF,Yau V,Zhang JY,Zhang XY,Yan YP,Cai ZG
14-9760 was used in Immunocytochemistry-immunoflourescence to identify heterogeneity in the tumour microenvironment of oral squamous cell carcinoma T1N0M0 samples which may contribute to poor early prognosis.
Sun Nov 01 00:00:00 EDT 2020
The vitamin D analogue calcipotriol promotes an anti-tumorigenic phenotype of human pancreatic CAFs but reduces T cell mediated immunity.
Scientific reports
Gorchs L,Ahmed S,Mayer C,Knauf A,Fernández Moro C,Svensson M,Heuchel R,Rangelova E,Bergman P,Kaipe H
Published figure using Alpha-Smooth Muscle Actin monoclonal antibody (Product # 14-9760-82) in Immunocytochemistry
Thu Oct 15 00:00:00 EDT 2020
The vitamin D analogue calcipotriol promotes an anti-tumorigenic phenotype of human pancreatic CAFs but reduces T cell mediated immunity.
Scientific reports
Gorchs L,Ahmed S,Mayer C,Knauf A,Fernández Moro C,Svensson M,Heuchel R,Rangelova E,Bergman P,Kaipe H
Published figure using Alpha-Smooth Muscle Actin monoclonal antibody (Product # 14-9760-82) in Immunocytochemistry
Thu Oct 15 00:00:00 EDT 2020
Acellular Gelatinous Material of Human Umbilical Cord Enhances Wound Healing: A Candidate Remedy for Deficient Wound Healing.
Frontiers in physiology
Bakhtyar N,Jeschke MG,Mainville L,Herer E,Amini-Nik S
14-9760 was used in Immunohistochemistry on paraffin embedded tissues to investigate the effects of treatment with acellular gelatinous Wharton's jelly on wound healing in vitro and in vivo.
Thu Oct 01 00:00:00 EDT 2020
Derivation of induced pluripotent stem cells (SDUKIi003-A) from a 20-year-old male patient diagnosed with Asperger syndrome.
Stem cell research
Kamand M,Ilieva M,Louise Forsberg S,Thomassen M,Meyer M,Fex Svenningsen Å,Maria Michel T
14-9760-82 was used in In vitro Assay to validate the expression of pluripotency markers, differentiation into the three germ layers, and absence of chromosomal abnormalities.
Thu Oct 01 00:00:00 EDT 2020
Regulatory T Cells Control the Switch From in situ to Invasive Breast Cancer.
Frontiers in immunology
Martinez LM,Robila V,Clark NM,Du W,Idowu MO,Rutkowski MR,Bos PD
Published figure using Alpha-Smooth Muscle Actin monoclonal antibody (Product # 14-9760-82) in Immunocytochemistry
Tue Sep 29 00:00:00 EDT 2020
Regulatory T Cells Control the Switch From in situ to Invasive Breast Cancer.
Frontiers in immunology
Martinez LM,Robila V,Clark NM,Du W,Idowu MO,Rutkowski MR,Bos PD
Published figure using Alpha-Smooth Muscle Actin monoclonal antibody (Product # 14-9760-82) in Immunocytochemistry
Tue Sep 29 00:00:00 EDT 2020
Asporin Reduces Adult Aortic Valve Interstitial Cell Mineralization Induced by Osteogenic Media and Wnt Signaling Manipulation In Vitro.
International journal of cell biology
Polley A,Khanam R,Sengupta A,Chakraborty S
14-9760 was used in Immunocytochemistry-immunoflourescence to study the Asporin function in aortic cusp mineralization and calcification.
Mon Sep 28 00:00:00 EDT 2020
Asporin Reduces Adult Aortic Valve Interstitial Cell Mineralization Induced by Osteogenic Media and Wnt Signaling Manipulation In Vitro.
International journal of cell biology
Polley A,Khanam R,Sengupta A,Chakraborty S
14-9760 was used in Immunocytochemistry-immunoflourescence to study the Asporin function in aortic cusp mineralization and calcification.
Mon Sep 28 00:00:00 EDT 2020
Physiologically Relevant Fluid-Induced Oscillatory Shear Stress Stimulation of Mesenchymal Stem Cells Enhances the Engineered Valve Matrix Phenotype.
Frontiers in cardiovascular medicine
Gonzalez BA,Perez-Nevarez M,Mirza A,Perez MG,Lin YM,Hsu CD,Caobi A,Raymond A,Gomez Hernandez ME,Fernandez-Lima F,George F,Ramaswamy S
Published figure using Alpha-Smooth Muscle Actin monoclonal antibody (Product # 14-9760-82) in Immunocytochemistry
Mon Sep 28 00:00:00 EDT 2020
Physiologically Relevant Fluid-Induced Oscillatory Shear Stress Stimulation of Mesenchymal Stem Cells Enhances the Engineered Valve Matrix Phenotype.
Frontiers in cardiovascular medicine
Gonzalez BA,Perez-Nevarez M,Mirza A,Perez MG,Lin YM,Hsu CD,Caobi A,Raymond A,Gomez Hernandez ME,Fernandez-Lima F,George F,Ramaswamy S
Published figure using Alpha-Smooth Muscle Actin monoclonal antibody (Product # 14-9760-82) in Immunocytochemistry
Mon Sep 28 00:00:00 EDT 2020
A Novel Model of Balloon Angioplasty Injury in Rat Arteriovenous Fistula.
Journal of vascular research
Somarathna M,Isayeva-Waldrop T,Al-Balas A,Guo L,Lee T
14-9760 was used in Immunohistochemistry to develop and characterize a rat model of arteriovenous fistula angioplasty injury.
Mon Sep 14 00:00:00 EDT 2020
A Novel Model of Balloon Angioplasty Injury in Rat Arteriovenous Fistula.
Journal of vascular research
Somarathna M,Isayeva-Waldrop T,Al-Balas A,Guo L,Lee T
14-9760 was used in Immunohistochemistry to develop and characterize a rat model of arteriovenous fistula angioplasty injury.
Mon Sep 14 00:00:00 EDT 2020
Direct reprogramming of human smooth muscle and vascular endothelial cells reveals defects associated with aging and Hutchinson-Gilford progeria syndrome.
eLife
Bersini S,Schulte R,Huang L,Tsai H,Hetzer MW
14-9760 was used in Immunohistochemistry-immunofluorescence to show that iVECs and iSMCs retain disease-related signatures, allowing modeling of vascular aging and HGPS in vitro.
Tue Sep 08 00:00:00 EDT 2020
Direct reprogramming of human smooth muscle and vascular endothelial cells reveals defects associated with aging and Hutchinson-Gilford progeria syndrome.
eLife
Bersini S,Schulte R,Huang L,Tsai H,Hetzer MW
14-9760 was used in Immunohistochemistry-immunofluorescence to show that iVECs and iSMCs retain disease-related signatures, allowing modeling of vascular aging and HGPS in vitro.
Tue Sep 08 00:00:00 EDT 2020
Differential effects of low-dose sacubitril and/or valsartan on renal disease in salt-sensitive hypertension.
American journal of physiology. Renal physiology
Polina I,Domondon M,Fox R,Sudarikova AV,Troncoso M,Vasileva VY,Kashyrina Y,Gooz MB,Schibalski RS,DeLeon-Pennell KY,Fitzgibbon WR,Ilatovskaya DV
14-9760-82 was used in Western Blot to investigate if increasing atrial natriuretic peptide levels with sacubitril, combined with renin-angiotensin system blockage by valsartan, can be beneficial for alleviation of renal damage in a model of salt-sensitive hypertension.
Wed Jul 01 00:00:00 EDT 2020
A new intrasurgical technique to safely and reproducibly induce partial unilateral urinary obstruction and renal scarring in a Rat Model.
International urology and nephrology
Vroomen LGPH,John NT,Fuijmori M,Sivaraman A,Felsen D,Srimathveeravalli G
14-9760-82 was used in Immunohistochemistry to evaluate whether irreversible electroporation can be used to induce urinary obstruction for a rat model of renal scarring.
Wed Jul 01 00:00:00 EDT 2020
Desmoplasia and oncogene driven acinar-to-ductal metaplasia are concurrent events during acinar cell-derived pancreatic cancer initiation in young adult mice.
PloS one
Johnson BL,d'Alincourt Salazar M,Mackenzie-Dyck S,D'Apuzzo M,Shih HP,Manuel ER,Diamond DJ
14-9760-82 was used in Immunohistochemistry to study acinar cell-derived pancreatic ductal adenocarcinoma (PDAC) initiation by developing a genetically engineered mouse model of PDAC.
Thu Mar 05 00:00:00 EST 2020
Low Incidence of High-Grade Pancreatic Intraepithelial Neoplasia Lesions in a Crmp4 Gene-Deficient Mouse Model of Pancreatic Cancer.
Translational oncology
Yazawa K,Nakamura F,Masukawa D,Sato S,Hiroshima Y,Yabushita Y,Mori R,Matsuyama R,Kato I,Taniguchi H,Goshima Y,Endo I
Published figure using Alpha-Smooth Muscle Actin monoclonal antibody (Product # 14-9760-82) in Immunohistochemistry
Sun Mar 01 00:00:00 EST 2020
Vascular smooth muscle TRPC3 channels facilitate the inverse hemodynamic response during status epilepticus.
Scientific reports
Cozart MA,Phelan KD,Wu H,Mu S,Birnbaumer L,Rusch NJ,Zheng F
14-9760 was used in Immunohistochemistry to show ablation of smooth muscle transient receptor potential 3 channels eliminates the secondary phase of intense seizures, consequently reducing the duration of status epilepticus.
Tue Jan 21 00:00:00 EST 2020
Vascular smooth muscle TRPC3 channels facilitate the inverse hemodynamic response during status epilepticus.
Scientific reports
Cozart MA,Phelan KD,Wu H,Mu S,Birnbaumer L,Rusch NJ,Zheng F
14-9760 was used in Immunohistochemistry to show ablation of smooth muscle transient receptor potential 3 channels eliminates the secondary phase of intense seizures, consequently reducing the duration of status epilepticus.
Tue Jan 21 00:00:00 EST 2020
Karyopherin Alpha 2-Expressing Pancreatic Duct Glands and Intra-Islet Ducts in Aged Diabetic C414A-Mutant-CRY1 Transgenic Mice.
Journal of diabetes research
Okano S,Yasui A,Kanno SI,Satoh K,Igarashi M,Nakajima O
14-9760 was used in Immunohistochemistry to study the expression of karyopherin alpha 2 in pancreatic ductal atypia and in normal pancreatic tissues.
Mon Jan 13 00:00:00 EST 2020
Perturbed myoepithelial cell differentiation in BRCA mutation carriers and in ductal carcinoma in situ.
Nature communications
Ding L,Su Y,Fassl A,Hinohara K,Qiu X,Harper NW,Huh SJ,Bloushtain-Qimron N,Jovanović B,Ekram M,Zi X,Hines WC,Alečković M,Gil Del Alcazar C,Caulfield RJ,Bonal DM,Nguyen QD,Merino VF,Choudhury S,Ethington G,Panos L,Grant M,Herlihy W,Au A,Rosson GD,Argani P,Richardson AL,Dillon D,Allred DC,Babski K,Kim EMH,McDonnell CH,Wagner J,Rowberry R,Bobolis K,Kleer CG,Hwang ES,Blum JL,Cristea S,Sicinski P,Fan R,Long HW,Sukumar S,Park SY,Garber JE,Bissell M,Yao J,Polyak K
14-9760-82 was used in Immunohistochemistry (Paraffin) to investigate myoepithelial cells in normal breast tissues of BRCA1 and BRCA2 germline mutation carriers and in non-carrier controls, and in sporadic DCIS.
Fri Sep 13 00:00:00 EDT 2019
Material-Induced Venosome-Supported Bone Tubes.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Charbonnier B,Baradaran A,Sato D,Alghamdi O,Zhang Z,Zhang YL,Gbureck U,Gilardino M,Harvey E,Makhoul N,Barralet J
Published figure using Alpha-Smooth Muscle Actin monoclonal antibody (Product # 14-9760-82) in Immunohistochemistry
Wed Sep 04 00:00:00 EDT 2019
Material-Induced Venosome-Supported Bone Tubes.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Charbonnier B,Baradaran A,Sato D,Alghamdi O,Zhang Z,Zhang YL,Gbureck U,Gilardino M,Harvey E,Makhoul N,Barralet J
Published figure using Alpha-Smooth Muscle Actin monoclonal antibody (Product # 14-9760-82) in Immunohistochemistry
Wed Sep 04 00:00:00 EDT 2019
YBX-1 mediated sorting of miR-133 into hypoxia/reoxygenation-induced EPC-derived exosomes to increase fibroblast angiogenesis and MEndoT.
Stem cell research & therapy
Lin F,Zeng Z,Song Y,Li L,Wu Z,Zhang X,Li Z,Ke X,Hu X
Published figure using Alpha-Smooth Muscle Actin monoclonal antibody (Product # 14-9760-82) in Western Blot
Fri Aug 23 00:00:00 EDT 2019
Highly multiplexed immunofluorescence imaging of human tissues and tumors using t-CyCIF and conventional optical microscopes.
eLife
Lin JR,Izar B,Wang S,Yapp C,Mei S,Shah PM,Santagata S,Sorger PK
Published figure using Alpha-Smooth Muscle Actin monoclonal antibody (Product # 14-9760-82) in Immunofluorescence
Wed Jul 11 00:00:00 EDT 2018
Human ISL1+ Ventricular Progenitors Self-Assemble into an In Vivo Functional Heart Patch and Preserve Cardiac Function Post Infarction.
Molecular therapy : the journal of the American Society of Gene Therapy
Foo KS,Lehtinen ML,Leung CY,Lian X,Xu J,Keung W,Geng L,Kolstad TRS,Thams S,Wong AO,Wong N,Bylund K,Zhou C,He X,Jin SB,Clarke J,Lendahl U,Li RA,Louch WE,Chien KR
Published figure using Alpha-Smooth Muscle Actin monoclonal antibody (Product # 14-9760-82) in Immunohistochemistry
Thu Jul 05 00:00:00 EDT 2018
Single-cell profiling reveals heterogeneity and functional patterning of GPCR expression in the vascular system.
Nature communications
Kaur H,Carvalho J,Looso M,Singh P,Chennupati R,Preussner J,Günther S,Albarrán-Juárez J,Tischner D,Classen S,Offermanns S,Wettschureck N
Published figure using Alpha-Smooth Muscle Actin monoclonal antibody (Product # 14-9760-82) in Flow Cytometry
Fri Jun 16 00:00:00 EDT 2017
Intranasal Curcumin Inhibits Pulmonary Fibrosis by Modulating Matrix Metalloproteinase-9 (MMP-9) in Ovalbumin-Induced Chronic Asthma.
Inflammation
Chauhan PS,Dash D,Singh R
14976082 was used in western blot to study the effect of intranasal curcumin on airway remodeling and fibrosis in murine model of chronic asthma
Wed Feb 01 00:00:00 EST 2017
Endothelial cells are progenitors of cardiac pericytes and vascular smooth muscle cells.
Nature communications
Chen Q,Zhang H,Liu Y,Adams S,Eilken H,Stehling M,Corada M,Dejana E,Zhou B,Adams RH
Published figure using Alpha-Smooth Muscle Actin monoclonal antibody (Product # 14-9760-82) in Immunofluorescence
Fri Aug 12 00:00:00 EDT 2016
Monoclonal antibodies against muscle actin isoforms: epitope identification and analysis of isoform expression by immunoblot and immunostaining in normal and regenerating skeletal muscle.
F1000Research
Chaponnier C,Gabbiani G
14-9760 was used in Immunofluorescence on frozen tissues to indicate that a restricted myocyte population expresses α-CAA and suggest a high capacity of self-regeneration in muscle cells.
Mon Jun 27 00:00:00 EDT 2016