|Tested species reactivity||Human, Mouse|
|Published species reactivity||Mouse, Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Synthetic peptide corresponding to residues L(18) E V P T D G N A G L L A E P Q I A M F C(38) of human Amyloid Precursor Protein.|
|Storage buffer||PBS with 10mg/ml sucrose|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||5-10 µg/ml|
|Western Blot (WB)||5-10 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA1-25489 detects Amyloid Precursor Protein from human samples.
MA1-25489 has been successfully used in Western blot and Immunohistochemistry (paraffin) procedures.
The MA1-25489 immunogen is a synthetic peptide corresponding to residues L(18) E V P T D G N A G L L A E P Q I A M F C(38) of human Amyloid Precursor Protein.
Amyloid Precurser Protein (APP) functions as a cell surface kinesin I membrane receptor, mediating the axonal transport of beta-secretase and presenilin 1; APP is rapidly internalized via clathrin-coated pits. APP is important for neurite growth, neuronal adhesion and azonogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Nogo-receptor 1 deficiency has no influence on immune cell repertoire or function during experimental autoimmune encephalomyelitis.
MA1-25489 was used in immunohistochemistry to study the effects of Nogo receptor-1 ablation on immune cell function in a murine model of autoimmune encaphalomyelitis
|Litwak SA,Payne NL,Campanale N,Ozturk E,Lee JY,Petratos S,Siatskas C,Bakhuraysah M,Bernard CC||PloS one (8:null)||2013|
Ran-independent nuclear import of cyclin B1-Cdc2 by importin beta.
MA1-25489 was used in immunoprecipitation to study the mechanism for the cyclin B1-Cdc2 import into the nucleus
|Takizawa CG,Weis K,Morgan DO||Proceedings of the National Academy of Sciences of the United States of America (96:7938)||1999|