|Tested species reactivity||Human, Mouse|
|Published species reactivity||Not Applicable|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to amino acid residues G L M V G G VV of human abeta 40.|
|Storage buffer||whole serum|
|Contains||0.05% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Western Blot (WB)||See 1 publications below|
Amyloid beta-protein (abeta) is associated with neuronal injury and death in Alzheimer's disease. These proteins are the main components of amyloid plaques.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
TrkB activation by 7, 8-dihydroxyflavone increases synapse AMPA subunits and ameliorates spatial memory deficits in a mouse model of Alzheimer's disease.
PA3-16760 was used in western blot to determine how an increase in synapse AMPA subuit and amelioration of spatial memory deficits occurs by TrkB activation by 7,8-dihydroxyflavone in a mouse model of Alzheimer's disease
|Gao L,Tian M,Zhao HY,Xu QQ,Huang YM,Si QC,Tian Q,Wu QM,Hu XM,Sun LB,McClintock SM,Zeng Y||Journal of neurochemistry (136:620)||2016|