Angiopoietin-2 (ANGPT2) is an antagonist of angiopoietin 1 (ANGPT1) and endothelial TEK tyrosine kinase (TIE-2, TEK). The protein disrupts the vascular remodeling ability of ANGPT1 and may induce endothelial cell apoptosis. Three transcript variants encoding three different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: AGPT2; ANG 2; ANG-2; ANG2; angiopoietin 2; Angiopoietin-2; angiopoietin-2a; angiopoietin-2B; ANGPT2; Tie2-ligand
Gene Aliases: AGPT2; Ang-2; ANG2; ANGPT2
Molecular Function: signaling molecule