PA5-34646 targets Angiopoietin 4 in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-34646 immunogen is recombinant protein fragment contains a sequence corresponding to a region within amino acids 1 and 108 (Q9Y264) of Angiopoietin 4.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
Binds to TEK/TIE2, modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2. Promotes endothelial cell survival, migration and angiogenesis.
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Protein Aliases: AGP4; ANG-3; ANG-4; ANG4; Angiopoietin-3; Angiopoietin-4
Gene Aliases: ANG3; ANG4; ANGPT4
UniProt ID: (Human) Q9Y264
Entrez Gene ID: (Human) 51378
Molecular Function: signaling molecule