This gene encodes a member of the annexin family, a group of calcium-dependent phospholipid-binding proteins. Annexins have unique N-terminal domains and conserved C-terminal domains, which contain the calcium-dependent phospholipid-binding sites. The encoded protein is a 56-kD antigen recognized by sera from patients with various autoimmune diseases. Transcript variants encoding the same isoform have been identified.
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Protein Aliases: 56 kDa autoantigen; Annexin A11; Annexin XI; Annexin-11; autoantigen, 56-kD; Calcyclin-associated annexin 50; CAP-50
Gene Aliases: ANX11; ANXA11; CAP50
UniProt ID: (Human) P50995
Entrez Gene ID: (Human) 311