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|Tested species reactivity||Bovine, Dog, Human, Sheep|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Annexin II purified from bovine lung.|
|Storage buffer||proprietary buffer|
|Contains||0.09% sodium azide|
|Tested Applications||Dilution *|
|ELISA (ELISA)||0.1-1.0 ug/ml|
|Immunohistochemistry (IHC)||5-10 ug/ml|
|Western Blot (WB)||0.5-1.0 ug/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Western Blot (WB)||See 2 publications below|
This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption. This gene has three pseudogenes located on chromosomes 4, 9 and 10, respectively. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
|Human||Not Cited||Annexin II mediates plasminogen-dependent matrix invasion by human monocytes: enhanced expression by macrophages.||Brownstein C,Deora AB,Jacovina AT,Weintraub R,Gertler M,Khan KM,Falcone DJ,Hajjar KA||Blood (103:317)||2004|
Suppressive effect on lymphoproliferation in vitro by soluble annexin II released from isolated placental membranes.
03-4400 was used in western blot to test if annexin II is released from syncytiotrophoblast microvillous plasma membranes and if it has any immunosuppressive effect.
|Aarli A,Kristoffersen EK,Jensen TS,Ulvestad E,Matre R||American journal of reproductive immunology (New York, N.Y. : 1989) (38:313)||1997|
annexin 2; annexin A2; annexin II; annexin-2; ANX2; ANX2L4; CAL1H; calpactin I heavy chain; calpactin I heavy polypeptide; calpactin-1 heavy chain; chromobindin 8; chromobindin-8; epididymis secretory protein Li 270; LIP2; lipocortin II; LPC2; LPC2D; p36; PAP-IV; placental anticoagulant protein IV; protein I
ANX2; ANX2L4; ANXA2; BOS_10772; CAL1H; HEL-S-270; LIP2; LPC2; LPC2D; P36; PAP-IV