This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated. View Details
Immunogen sequence: LVVLLQANRD PDAGIDEAQV EQDAQALFQA GELKWGTDEE KFITIFGTRS VSHLRKVFDK YMTISGFQIE ETIDRETSGN LEQLLLAVVK SIRSIPAYLA ETLYYAMKGA G
Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 94%.
The protein encoded by this gene belongs to the annexin family of calcium-dependent phospholipid binding proteins some of which have been implicated in membrane-related events along exocytotic and endocytotic pathways. Annexin 5 is a phospholipase A2 and protein kinase C inhibitory protein with calcium channel activity and a potential role in cellular signal transduction, inflammation, growth and differentiation. Annexin 5 has also been described as placental anticoagulant protein I, vascular anticoagulant-alpha, endonexin II, lipocortin V, placental protein 4 and anchorin CII. The gene spans 29 kb containing 13 exons, and encodes a single transcript of approximately 1.6 kb and a protein product with a molecular weight of about 35 kDa.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Anchorin CII; Annexin A5; Annexin V; Annexin-5; Calphobindin I; CBP-I; Endonexin II; epididymis secretory protein Li 7; Lipocortin V; PAP-I; Placental anticoagulant protein 4; Placental anticoagulant protein I; PP4; Thromboplastin inhibitor; VAC-alpha; Vascular anticoagulant-alpha
Gene Aliases: ANX5; ANXA5; ENX2; HEL-S-7; PP4; R74653; RPRGL3
Molecular Function: calcium-binding protein