|Tested species reactivity||Human, Non-human primate|
|Host / Isotype||Mouse / IgG1|
|Immunogen||This information is considered to be commercially sensitive.|
|Purification||Size-exclusion - Gel filtration|
|Storage buffer||0.01M sodium phosphate, pH 7.4, with 0.15M NaCl|
|Contains||0.01% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|ELISA (ELISA)||1-5 µg/ml|
|Western Blot (WB)||1-5 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA1-27334 detects Antithrombin III from human and baboon samples. MA1-27334 will not react with rabbit, bovine, or canine.
MA1-27334 has been successfully used in Blocking, Western blot and ELISA procedures.
The MA1-27334 immunogen is considered to be commercially sensitive.
The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.