A suggested positive control is chicken liver lysate.
PA5-21166 can be used with blocking peptide PEP-1280.
Apolipoprotein A1 (ApoA1) is the major protein component of high density lipoprotein (HDL) in plasma, which is correlated with cardiovascular disease. ApoA1 is synthesized in the liver and small intestine and promotes cholesterol efflux from tissues to the liver for excretion. It is a cofactor for lecithin cholesterolacyltransferase (LCAT), the enzyme responsible for the formation of most plasma cholesteryl esters. Defects in ApoA1 are associated with HDL deficiency, Tangier disease, and systemic non-neuropathic amyloidosis.
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Protein Aliases: Apo-AI; apoA-I; Apolipoprotein A-I; Apolipoprotein A-I(1-242); Apolipoprotein A1; ProapoA-I; Proapolipoprotein A-I; Truncated apolipoprotein A-I
Gene Aliases: apo(a); APOA1