By sandwich ELISA, MA5-14732 can be used to detect Apo A-1 from serum samples. To increase sensitivity of sandwich ELISAs with MA5-14732, a biotinylated detection antibody followed by Streptavidin-HRP is recommended. By Western blot, MA5-14732 detects recombinant human Apo A-1, but not recombinant mouse Apo A-1. MA5-14732 is also recommended for detecting endogenous Apo A-1 by Western blot.
By Western blot, MA5-14732 detects recombinant human Apo A-1, but not recombinant mouse Apo A-1. MA5-14732 is also recommended for detecting endogenous Apo A-1 by Western blot.
Product MA514732 is a smaller package size of MIA1405 (formerly sold as a Seradyn product).
This gene encodes apolipoprotein A-I, which is the major protein component of high density lipoprotein (HDL) in plasma. The protein promotes cholesterol efflux from tissues to the liver for excretion, and it is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. This gene is closely linked with two other apolipoprotein genes on chromosome 11. Defects in this gene are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Apo-AI; apoA-I; Apolipoprotein A-I; Apolipoprotein A-I(1-242); Apolipoprotein A1; ProapoA-I; Proapolipoprotein A-I; Truncated apolipoprotein A-I
Gene Aliases: apo(a); APOA1
UniProt ID: (Human) P02647
Entrez Gene ID: (Human) 335