This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details
By sandwich ELISA, MIA1405 can be used as a detection antibody with Product # 710263 or # 701239 as a coating antibody, to generate a matched pair. Using these matched pairs, recombinant human Apo A-1, but not recombinant mouse Apo A-1, was detected. MIA1405 can be used to detect Apo A-1 from serum samples. To increase sensitivity of sandwich ELISAs with MIA1405, a biotinylated detection antibody followed by Streptavidin-HRP is recommended.
By Western blot, MIA1405 detects recombinant human Apo A-1, but not recombinant mouse Apo A-1. MIA1405 is also recommended for detecting endogenous Apo A-1 by Western blot.
MIA1405 was formerly sold as a Seradyn product.
This gene encodes apolipoprotein A-I, which is the major protein component of high density lipoprotein (HDL) in plasma. The protein promotes cholesterol efflux from tissues to the liver for excretion, and it is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. This gene is closely linked with two other apolipoprotein genes on chromosome 11. Defects in this gene are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Apo-AI; apoA-I; Apolipoprotein A-I; Apolipoprotein A-I(1-242); Apolipoprotein A1; ProapoA-I; Proapolipoprotein A-I; Truncated apolipoprotein A-I
Gene Aliases: Alp-1; apo(a); apo-AI; Apoa-1; apoA-I; APOA1; Brp-14; Ltw-1; Lvtw-1; Sep-1; Sep-2; Sep2