|Tested species reactivity||Mouse, Rat|
|Published species reactivity||Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Purified mouse apolipoprotein AI from pooled mouse plasma high density lipoprotein.|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 8, with 1mM EDTA|
|Contains||0.02% sodium azide|
|Storage Conditions||4° C, do not freeze|
|Tested Applications||Dilution *|
|ELISA (ELISA)||Assay dependent|
|Western Blot (WB)||Assay dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Western Blot (WB)||See 1 publications below|
PA1-23059 detects apolipoprotein A1 in mouse and rat samples. This antibody does not cross-react with human Apolipoprotein A1.
PA1-23059 has been successfully used in ELISA, Radial immunodiffusion assays, and Western blot procedures. Predicted molecular weight of 31 kDa.
The PA1-23059 immunogen is purified mouse apolipoprotein AI from pooled mouse plasma high density lipoprotein.
Apolipoprotein A I promotes cholesterol efflux from tissues to the liver for excretion. Apolipoprotein A I is the major protein component of high density lipoprotein (HDL) in the plasma. Synthesized in the liver and small intestine, it consists of two identical chains of 77 amino acids; an 18 amino acid signal peptide is removed co-translationally and a 6 amino acid propeptide is cleaved post-translationally. Apolipoprotein A I is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. Defects in the Apolipoprotein A I gene are associated with HDL deficiency and Tangier disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
A thermally stable form of bacterial cocaine esterase: a potential therapeutic agent for treatment of cocaine abuse.
PA1-23059 was used in western blot to investigate the therapeutic potential of Rhodococcal cocaine esterase in the treatment of cocaine abuse
|Brim RL,Nance MR,Youngstrom DW,Narasimhan D,Zhan CG,Tesmer JJ,Sunahara RK,Woods JH||Molecular pharmacology (77:593)||2010|