|Tested species reactivity||Hamster, Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Full length, native protein purified from hamster plasma high density lipoprotein.|
|Storage buffer||100U/ml Penicillin|
|Contains||25ng/ml Amphotericin B, 0.05% sodium azide, 10µg/ml Streptomycin|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Immunodiffusion (IDF)||Assay Dependent|
|Western Blot (WB)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-27156 detects Apolipoprotein A I from hamster samples.
PA1-27156 has been successfully used in Western blot, double immunodiffusion and radial immunodiffusion procedures. The predicted molecular weight is 31 kDa.
The PA1-27156 immunogen is full length, native protein purified from hamster plasma high density lipoprotein.
Apolipoprotein A I promotes cholesterol efflux from tissues to the liver for excretion. Apolipoprotein A I is the major protein component of high density lipoprotein (HDL) in the plasma. Synthesized in the liver and small intestine, it consists of two identical chains of 77 amino acids; an 18 amino acid signal peptide is removed co-translationally and a 6 amino acid propeptide is cleaved post-translationally. Apolipoprotein A I is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. Defects in the Apolipoprotein A I gene are associated with HDL deficiency and Tangier disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.