Apolipoprotein A4 (also known as ApoA-IV) is a plasma protein that is an O-linked glycoprotein after proteolytic processing. ApoA4 is a major constituent of HDL and it also can be found on the surface of newly synthesized chylomicrons. The physiological function of ApoA4 is not completely identified so far, but evidence from several in vitro studies indicate that this apolipoprotein is involved in several steps of the reverse cholesterol transport pathway, which transports cholesterol from peripheral cells back to the liver.
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Protein Aliases: Apo-AIV; apoA-IV; Apolipoprotein A-IV; Apolipoprotein A4; MGC142154; MGC142156
Gene Aliases: APOA4
UniProt ID: (Human) P06727
Entrez Gene ID: (Human) 337
Molecular Function: apolipoprotein