MA5-15265 targets APOA5 in IF and WB applications and shows reactivity with Human samples.
The MA5-15265 immunogen is purified recombinant fragment of human Apoa5 expressed in E. Coli.
The protein encoded by this gene is an apolipoprotein that plays an important role in regulating the plasma triglyceride levels, a major risk factor for coronary artery disease. It is a component of high density lipoprotein and is highly similar to a rat protein that is upregulated in response to liver injury. Mutations in this gene have been associated with hypertriglyceridemia and hyperlipoproteinemia type 5. This gene is located proximal to the apolipoprotein gene cluster on chromosome 11q23. Alternatively spliced transcript variants encoding the same protein have been identified.
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Protein Aliases: Apo-AV; APOA-V; APOA5; APOAV; Apolipoprotein A-V; apolipoprotein A-V precursor variant 3; Apolipoprotein A5; MGC126836; MGC126838; RAP3; Regeneration-associated protein 3
Gene Aliases: APOA5; APOAV; RAP3; UNQ411/PRO773
UniProt ID: (Human) Q6Q788
Entrez Gene ID: (Human) 116519