MA5-15487 targets APOL1 in WB applications and shows reactivity with Human samples.
The MA5-15487 immunogen is purified recombinant fragment of APOL1 expressed in E. Coli.
MA5-15487 detects APOL1 which has a predicted molecular weight of approximately 44kDa.
This gene encodes a secreted high density lipoprotein which binds to apolipoprotein A-I. Apolipoprotein A-I is a relatively abundant plasma protein and is the major apoprotein of HDL. It is involved in the formation of most cholesteryl esters in plasma and also promotes efflux of cholesterol from cells. This apolipoprotein L family member may play a role in lipid exchange and transport throughout the body, as well as in reverse cholesterol transport from peripheral cells to the liver. Several different transcript variants encoding different isoforms have been found for this gene.
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Protein Aliases: APO-L; APOL; APOL- I; ApoL-I; Apolipoprotein L; apolipoprotein L 1; apolipoprotein L, 1; Apolipoprotein L-I; Apolipoprotein L1
Gene Aliases: APO-L; APOL; APOL-I; APOL1; FSGS4
UniProt ID: (Human) O14791
Entrez Gene ID: (Human) 8542